Seattle -4.5, under 46
There's not a metric I look at that favors the Patriots, not one. This does not feel like a competitive game to me. I think a giant blowout is more likely than a Patriots win. If you tell me the Seahawks with this game by 4 touchdowns, I'd get that. I just do not see an area of Patriots advantage sufficient for a win, other than injury variance. Not an appealing game, nor appealing outcome from the perspective of a 49ers fan. Nonetheless.